CD90 antibody

Catalog No. ABIN371025

This anti-CD90 antibody is a Rat Monoclonal antibody detecting CD90 in FACS, IHC (fro) and Func. Suitable for Mouse.

Quick Overview for CD90 antibody (ABIN371025)

Target: CD90 (THY1)

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD90 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Clone: G7

Product Details anti-CD90 Antibody

Specificity: This antibody recognises Thy-1.1 and Thy-1.2 alloantigens (Thy-1 epitope region A). MAb G7 stimulates T-cell proliferation and IL-2 secretion, via signalling through the T-cell receptor/CD3 complex. (Ref.1,5-7). It has also been reported to promote apoptosis of thymocytes and CTL clones (Ref.4,7) and to mediate adhesion of thymocytes to thymic stroma. (Ref.8)

Characteristics: Synonyms: Thy-1, THY1, CDw90, Thy-1 membrane glycoprotein

Purification: Purified

Isotype: IgG2c

Application Details

Application Notes: Flow Cytometry. (Ref.1,10)Immunohistochemistry (Acetone-Fixed, Frozen Sections). (Ref.10)In vitro T Cell Activation. (Ref.1,5,6,9)Induction of apoptosis.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CD90

Target: CD90 (THY1)

Alternative Name: CD90

Background: CD90/Thy-1, a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily of cell surface receptors, consists of a single V-set domain. (Ref.1-4) It is expressed on thymocytes, peripheral T lymphocytes, some intraepithelial T lymphocytes and neurons of all mouse strains. (Ref.1,2)Synonyms: CDw90, THY1, Thy-1, Thy-1 membrane glycoprotein

Gene ID: 21838

UniProt: P01831

Pathways: Cell-Cell Junction Organization